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The Eye Clinic: Montana's #1 LASIK Center

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"Dr Smith did an excellent job and I can see better than I have for a long time." - Vic Redinger

"I recommend the Eye Clinic to anyone who needs their eyes repaired" - Bobbi Domeko

"I am still pinching myself after LASIK - it feels like a miracle." - Traci Nelson Anderson

"From the time we walked in, everyone was very friendly, informative, and professional." - SV: Clearmont, WY

"I wanted to compliment your entire staff, from the front desk to your assistant…showed calmness and friendliness" - Patient of Dr. LaGreca

Collagen Crosslinking

I am pleased to announce that our cornea clinic has been chosen to participate in a Multi-Center, Randomized, Controlled Evaluation of the Safety and Efficacy of the KXL System with VibeX (Riboflavin Ophthalmic Solution) for Corneal Collagen Cross-Linking in Eyes with Keratoconus or Corneal Ectasia after Refractive Surgery.

My Thanks in Advance,
C. Byron Smith, M.D.

We are now ready to begin enrolling patients. We have received authorization to enroll no more than 40 patients who will be enrolled on a first come first served basis. To be included patients should meet the following criterion:

CriteriaConsiderationsEligibilitySelection of PatientsCosts
All Patients enrolled must meet all of the following:
Be at least 12 years of age, male or female, of any race
Willingness and ability to follow all instructions and comply with schedule for follow-up visits
BSCVA of < 20/80
Presence of central or inferior steepening on the topographic map
Contact Lens Wearers Only: Removal of contact lenses is required for a 1 week period prior to the screening refraction and manifest refraction must be stable between two visits which occur at least 7 days apart.
Keratoconus Patients
Maximum corneal curvature as measured by a Kmax value ≥ 47.00 D
Axial topography consistent with keratoconus with marked areas of steepening
Ectasia Patients
Ectasia after refractive surgery
Axial topography consistent with ectasia
Pregnant or nursing females or those planning a pregnancy or having a positive urine pregnancy test prior to the treatment of either eye or during the course of the study;
Corneal pachymetry that is < 375 microns prior to epithelial debridement at the thinnest point in the eye to be treated;
Eyes which are aphakic;
Eyes which are pseudophakic AND do not have a UV blocking lens
Eyes that have the maximum corneal curvature (Kmax), as identified
and measured by topography, outside of the central 5mm zone;
Previous ocular condition (other than refractive error)
A history of delayed epithelial healing in the eye(s) to be treated;
Patients with a current condition that, in the investigator’s opinion,
would interfere with or prolong epithelial healing;
A history of previous Limbal Relaxing Incision (LRI) procedure
Previous corneal surgery, scars or the insertion of Intacs

For the present, we are only enrolling patients who meet the above criterion bilaterally unless the diagnosis is ectasia. Following the per-treatment visit (Day -45 to Day -1), eyes will be randomized (Day 0) to one of the three treatment groups. All treated eyes will be assessed at 1 day, 1 week, 1, 3, 6, and 12 months after collagen crosslinking.

For the present, we are only enrolling patients who meet the above criterion bilaterally unless the diagnosis is ectasia. Following the per-treatment visit (Day -45 to Day -1), eyes will be randomized (Day 0) to one of the three treatment groups. All treated eyes will be assessed at 1 day, 1 week, 1, 3, 6, and 12 months after collagen crosslinking.
Patients will be randomized among treatment groups with treatment times ranging from 2 to 8 minutes. No control patients will be randomized at this center, all enrollees will be treated.

After the 3 month examination of the study eye but no later than the 6 month examination window, subjects whose fellow eye meets all inclusion criteria and none of the exclusion criteria for performing the collagen crosslinking treatment will be given the option of having cross-linking performed on their fellow eye using the same treatment regimen performed on the study eye. After treatment, treated fellow eyes will be followed for 12 months according to the same schedule and protocol as the study eyes.
All enrollees will be subject to the approval of the chief investigator..

The collagen crosslinking treatment will be provided at no charge , however [our examination, evaluation and followup charges will be $1021.00 per eye. We will be happy to file for insurance payment of pre and post operative visits, however the patient will be responsible for the entire amount.

If you have a patient with special financial circumstances , feel free to discuss it with me personally and I will try to find a way to fund the treatment.

If you have questions regarding enrollment or eligibility of patients for this study I can be reached on my cell at 406-850-3102. Feel free to use this number any time you need consultation regarding corneal problems of any kind or if you need to refer a patient with a corneal problem for evaluation or care. Also feel free to tell us how our comprehensive cornea service can better serve your clinical needs.

CloseTo enroll a patient call Tammy at 406-252-6608

Enroll a Patient Today

To enroll a patient call Susanne Earpenbach at 406-252-6608

What is Collagen Crosslinking

Corneal collagen cross-linking is a technique which uses UV light and a photosensitizer to strengthen chemical bonds in the cornea. The goal of the treatment is to halt progressive and irregular changes in corneal shape known as ectasia. These ectatic changes are typically marked by corneal thinning and an increase in the anterior and/or posterior curvatures of the cornea, and often lead to high levels of myopia and astigmatism. The most common form of ectasia is keratoconus and less often ectasia is seen after laser vision correction such as LASIK. >> Read More @ EyeWiki
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