Official Test Study for Collagen Cross-Linking: Keratoconus or Corneal Ectasia

Official Test Study for Collagen Cross-Linking: Keratoconus or Corneal Ectasia

By EyeClinicAdmin November 16, 2012

We have been approved for a test study on Collagen Cross-Linking in Eyes with Keratoconus or Corneal Ectasia after Refractive Surgery, and we are now an official research clinic! Studies are already underway, contact us today to see if you qualify. Please see the following criteria:

[accordion title=”Criteria”]
All Patients enrolled must meet all of the following:

  • Be at least 12 years of age, male or female, of any race
  • Willingness and ability to follow all instructions and comply with schedule for follow-up visits
  • BSCVA of < 20/80
  • Presence of central or inferior steepening on the topographic map
  • Contact Lens Wearers Only: Removal of contact lenses is required for a 1 week period prior to the screening refraction and manifest refraction must be stable between two visits which occur at least 7 days apart.
  • Keratoconus Patients
  • Maximum corneal curvature as measured by a Kmax value ≥ 47.00 D
  • Axial topography consistent with keratoconus with marked areas of steepening
  • Ectasia Patients
  • Ectasia after refractive surgery
  • Axial topography consistent with ectasia

[accordion title=”Ineligible Patients”]
Ineligible Patients:

  • Contraindications, sensitivity or known allergy to the test article(s) or their components;
  • Pregnant or nursing females or those planning a pregnancy or having a positive urine pregnancy test prior to the treatment of either eye or during the course of the study;
  • Corneal pachymetry that is < 375 microns prior to epithelial debridement at the thinnest point in the eye to be treated;
  • Eyes which are aphakic;
  • Eyes which are pseudophakic AND do not have a UV blocking lens
  • Eyes that have the maximum corneal curvature (Kmax), as identified
  • and measured by topography, outside of the central 5mm zone;
  • Previous ocular condition (other than refractive error)
  • A history of delayed epithelial healing in the eye(s) to be treated;
  • Patients with a current condition that, in the investigator’s opinion,
  • would interfere with or prolong epithelial healing;
  • A history of previous Limbal Relaxing Incision (LRI) procedure
  • Previous corneal surgery, scars or the insertion of Intacs

[accordion title=”Other Considerations”]
Other Considerations:
For the present, we are not enrolling patients in a study so we do not know the specifics, if any, yet.


[message_box type=”note” icon=”yes” close=”Close”]Have questions? Contact Susanne Earpenbach at 406-252-6608[/message_box]

My Thanks in Advance,
C. Byron Smith, M.D.


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